In 2024, billionaire Mark Cuban campaigned for Vice President Kamala Harris. Now he’s praising one of President Donald Trump’s major affordability initiatives. In an X post, Cuban defended TrumpRx, Trump’s prescription drug program that allows consumers to buy directly from manufacturers to save up to 90 percent off the list price of commonly-purchased medications. “Everyone wants me to rip on TrumpRx,” Cuban said. But the “reality is, it’s saving patients money on IVF and a few other drugs [a] lot of money…anything that saves patients money is a win.”
Cuban told the Reporter in his latest interview that he wants to see more, not less, of TrumpRx. “They are set up to add more than one thousand drugs from CostPlusDrugs.com,” he said. But, “they have not told us when or if they will.”
The TrumpRx program has received widespread praise from consumers and business leaders, and some criticism from multiple news outlets. Cuban told the Reporter he attributes the negative press coverage to “the usual partisan politics and the fact there is not a lot of medicine on the list yet.”
While Cuban “can’t speak” to Trump’s Federal Trade Commission (FTC), he offered some criticisms and suggested the agency go further in addressing the monopolistic power of healthcare companies.
“They have not broken up the big insurance companies yet, so I don’t think they are getting it done in the health care space,” Cuban told the Reporter. “Their settlements so far have been uneventful.”
For years, Cuban has made major moves in the health care space, which gives him a unique vantage point into the inner workings of TrumpRx. “They truly do have some great people that are making smart moves, you just don’t know their names: Chris Klomp. Mark Atalla, Abe Sutton and so many more. When you talk to them, and see the work they put in, it’s obvious they are focused on trying to do the right thing for patients. Don’t forget they didn’t give the insurance industry a price increase they wanted, and those stock prices got crushed.”
Cuban’s CostPlugDrugs.com launched four years ago; he told the Reporter that he currently has “no plans” to take it public.
While Cuban is a fan of a lot of Trump’s work in the health care space, he isn’t becoming a Republican. He told the Reporter that in his home state of Texas, he “like[s] James Talarico,” who will run against either Sen. John Cornyn (R., Texas) or Attorney General Ken Paxton.
Below is a transcript of our interview with Mark Cuban, lightly edited for clarity.
Washington Reporter:
Do you think that TrumpRx should be expanded to cover more drugs?
Mark Cuban:
Yes. They are set up to add more than one thousand drugs from CostPlusDrugs.com. They have not told us when or if they will.
Washington Reporter:
What do you attribute the negative press coverage to?
Mark Cuban
The usual partisan politics and the fact there is not a lot of medicine on the list yet.
Washington Reporter:
How do you think the Trump FTC is doing so far?
Mark Cuban:
I can’t speak to the FTC. They have not broken up the big insurance companies yet, so I don’t think they are getting it done in the health care space. Their settlements so far have been uneventful.
Washington Reporter:
When do you plan on taking Cost Plus Drugs public?
Mark Cuban:
No plans.
Washington Reporter:
What races are you particularly excited about in 2026?
Mark Cuban:
The NBA race and the hopefully Indiana’s race to another CFP run.
Washington Reporter:
And what about in politics? Are there any candidates who are on your radar that you view as being more under the radar than you think they should be?
Mark Cuban:
I like James Talarico.
Washington Reporter:
Mark, thanks as always for your time.
